Blood Metabolomic Phenotyping of Dry Cows Could Predict the High Milk Somatic Cells in Early Lactation—Preliminary Results

Subclinical mastitis (SCM) is a very common disease of dairy cows. Currently, somatic cell count (SCC) used for SCM diagnoses. There are no prognostic tests to detect which cows may develop during the dry-off period. Therefore, objectives this study were identify metabolic alterations in serum pre-SCM period, at −8 and −4 weeks before calving, through targeted mass spectrometry (MS) assay. Fifteen cows, free any disease, 10 affected only by postpartum served as controls (CON) group, respectively. Results showed 59 47 metabolites that differentiated (p ≤ 0.05) CON –8 prior expected date parturition, Regression analysis indicated panel four (AUC = 0.92, p < 0.001) another 0.01) parturition might serve predictive biomarkers SCM. Early identification susceptible can enable development better preventive measurements ahead occurrence.